Ad hoc announcement pursuant to Art. 53 LR

• Audited full year 2022 annual financial figures due to be reported by end of May 2023

Basel, Switzerland, May 5, 2023 – Kinarus Therapeutics Holding AG (“Kinarus”) (SIX: KNRS), a clinical-stage biopharmaceutical company developing novel therapeutics to treat viral, respiratory and ophthalmic diseases, today reported unaudited key financial figures for the year ended 31 December 2022 of Kinarus Therapeutics Group. The audited full year 2022 financial figures are due to be reported by end of May 2023

On 28 April 2023, Kinarus announced that the SIX Exchange Regulation ("SER") approved a deadline extension until the end of May 2023 for the publication of the Kinarus’ 2022 annual report. In its decision, SER asked Kinarus to report unaudited key financial figures for the consolidated financial statements of Kinarus Therapeutics Group for the year ended 31 December 2022 by 5 May 2023. In compliance with SER’s request, Kinarus reported the following figures which have been prepared on a going concern basis.

Unaudited Key Financial Figures for the Year Ended 31 December 2022 for the Consolidated Financial Statements of Kinarus Therapeutics Group

Kinarus is currently finalizing the full year 2022 consolidated financial statements, including its subsidiaries, as well as the other elements of the annual report as required for the financial reporting requirements. Ernst & Young, Kinarus’ auditor is currently working on the audit of the consolidated financial statements prior to their reporting due by end of May 2023.

Kinarus Therapeutics Holding AG (www.kinarus.com) was founded in 2017 by experienced pharmaceutical executives in Basel, Switzerland. The Kinarus team utilizes its knowledge and drug development competencies to in-license and develop mid-stage clinical assets in which they have identified an increased probability of clinical and regulatory success and a rapid path to market. Kinarus possesses the exclusive worldwide license to pamapimod, covering all indications, and has patented KIN001, its novel mechanism in combination with pioglitazone.

THIS PRESS RELEASE DOES NOT CONSTITUTE AN OFFER TO SELL NOR AN INTIMATION TO SUBMIT A PROPOSAL FOR THE ACQUISITION OF SECURITIES OF KINARUS THERAPEUTICS HOLDING AG. THIS PRESS RELEASE IS NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, DIRECTLY OR INDIRECTLY, IN WHOLE OR IN PART, INTO OR WITHIN ANY JURISDICTION WHERE IT IS UNLAWFUL TO BE DISTRIBUTED.